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Published by Karger, S. Karger Mär 2022, 2022
ISBN 10: 3318070831ISBN 13: 9783318070835
Seller: Smartbuy, Einbeck, Germany
Book
Taschenbuch. Condition: Neu. Neuware - Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood coagulation system. In most cases, a lack of the ADAMTS13 enzyme leads to an accumulation of ultra-large von Willebrand factor molecules in the plasma which, in turn, initiate the formation of microscopic thromboses in small blood vessels. TTP is a medical emergency. Timely diagnosis and urgent and effective management are vital - mortality in those untreated is in the region of 90%.The understanding of TTP pathogenesis has increased markedly in recent decades. It is now known that TTP is acquired (immunemediated) or congenital, and that the most common type - the acquired form - predominantly affects women in their 40s. It is also clear that the prompt delivery of plasma exchange saves lives. 'Fast Facts: Thrombotic Thrombocytopenic Purpura' sets out, in a clear and accessible format, the steps to suspecting, diagnosing and treating this potentially devastating disease. These steps are complemented by clear descriptions of the disease mechanism and epidemiology. Differential diagnosis, which is of the utmost importance for this disease, is explored in detail. 32 pp. Englisch.
Published by Karger, S. Karger Mär 2022, 2022
ISBN 10: 3318070106ISBN 13: 9783318070101
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book
Taschenbuch. Condition: Neu. Neuware - Despite an overall decrease in tobacco use, lung cancer (80-85% of which is non-small-cell lung cancer [NSCLC]) is still the leading cause of cancer death in both men and women worldwide. Annual low-dose CT screening of high-risk individuals has the potential to detect early-stage tumors, which can usually be successfully treated with a combination of surgery, radiotherapy, and chemotherapy and, in some cases, targeted therapy. However, most patients with NSCLC still present with advanced or metastatic disease. For these patients, initial therapy is guided by the tumor's molecular characteristics and patient's performance status. Targeted therapies have significantly improved clinical outcomes and, for some patients with no targetable genetic alterations, immunotherapy has demonstrated significant overall survival benefit. This insightful guide is designed to bring you up to speed with the latest developments and is important reading for all health professionals and medical trainees working in this fast-moving field. Table of Contents: -Prevention and screening -Diagnosis and staging -Surgery -Radiotherapy -Systemic therapy in non-metastatic NSCLC -Systemic therapy in advanced-stage/metastatic disease without a molecular driver -Personalized treatment in advanced NSCLC -Oligometastatic disease and brain metastases.
Published by Karger, S. Karger Mär 2022, 2022
ISBN 10: 3318023795ISBN 13: 9783318023794
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book
Taschenbuch. Condition: Neu. Neuware - Excessive daily sleepiness associated with obstructive sleep apnea is a multifaceted complaint that usually involves disabling symptoms. Despite being a common complaint, best practice regarding the management of patients is not well defined, and failure to recognize the severity of the effects of symptoms on quality of life results in underdiagnosis, preventing patients from receiving adequate treatment. 'Fast Facts: Excessive Daily Sleepiness Associated with Obstructive Sleep Apnea' discusses the difficulties in formulating a single definition of excessive daily sleepiness that appropriately considers the experiences and features of daytime sleepiness, alongside an up-to-date overview of how to accurately assess patients, and ensure effective management and support. Table of Contents: -Epidemiology and etiology -Clinical features and diagnosis -Management -Patient impact and support.
Published by Karger, S. Karger Mär 2022, 2022
ISBN 10: 3318070742ISBN 13: 9783318070743
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book
Taschenbuch. Condition: Neu. Neuware - Chronic kidney disease-associated pruritus, also known as uremic pruritus and in this book called 'kidney itch', is defined as itching suffered by people with chronic kidney disease who have no other condition to explain it. Repeated scratching causes trauma, bleeding and, eventually, scarring of the skin. Kidney itch can also have far-reaching effects on quality of life, with patients' work and social life commonly affected. Even though kidney itch is common, it often goes undiagnosed, and when recognized, it is often inadequately treated or not treated at all. 'Fast Facts: Kidney Itch' describes the problem of kidney itch in detail, documents its impact on people's lives, reviews the current understanding of its pathophysiology, and then sets out an evidence-based approach to its assessment and management. Table of Contents: -Clinical features -Causes -How common is kidney itch and who is most at risk -The wider impact -Approach to management.
Published by Karger, S. Karger Mär 2022, 2022
ISBN 10: 3318070505ISBN 13: 9783318070507
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book
Taschenbuch. Condition: Neu. Neuware.
Published by Karger, S. Karger Mär 2022, 2022
ISBN 10: 3318069124ISBN 13: 9783318069129
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book
Buch. Condition: Neu. Neuware - Individual susceptibility to disease (i.e., one's own genetic background) is one of the three main components classically described in the etiology of dental caries. Hence, genes influence susceptibility to erosive tooth wear, dental development, and response to treatments and interventions. This publication is an up-to-date overview of individual susceptibility to dental caries, erosive tooth wear, and disturbances of dental development from different clinically relevant perspectives. One of the most recognized scientists in this field reports on recent research relating to human genetics - from general summaries to recommendations for daily clinical work and population-level interventions. This book covers all aspects of individual susceptibility to dental caries and erosive tooth wear. Several chapters deal with potential biological mechanisms, with additional ones providing a strong foundation in human genetics, and other chapters touch on efficacy of therapies and alternative concepts. This book is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on dental caries and erosive tooth wear.